Assessment of Natural Killer Cells in Tissues from Patients with Cervical Abnormalities
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چکیده
Objectives: The cellular immune system mediated by cytotoxic T lymphocytes (CTLs) and Natural killer (NK) cells are thought to play an important role in the ultimate decline of Squamous Intraepithelial Lesions (SILs). In this study, Natural killer and granzyme B (GranzB) positive T-cells were quantitatively evaluated in cervical tissuesamples obtained from women exhibiting invasive cancer (n= 5) and progressive grades of Cervical Intraepithelial, (CIN)I (n= 5), CINII (n= 5) and CINIII (n= 5), in addition to five normal controls.
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